Johne’s Still a Costly Animal Health Problem in Dairies
Recent research shows how it can be effectively controlled.
Johne’s disease continues to be a costly economic challenge for dairy producers. But results from recent long-term, on-farm research trials in Wisconsin have shown that there is no good reason this disease can’t be reined in. Mike Collins, DVM, PhD, a professor and researcher at the University of Wisconsin School of Veterinary Medicine, says recent results from trials begun in 2002, on nine commercial dairies, showed that Johne’s disease can be cost-effectively controlled and possibly eradicated.

Dr. Collins believes the time has come for the dairy industry to be proactive in controlling the spread of Johne’s in order to reduce the cost of its treatment. Results from the 2007 USDA National Animal Health Monitoring System (NAHMS) Dairy Survey indicated that 68 percent of U.S. dairy herds were infected with
mycobacterium paratuberculosis, the organism that causes Johne’s disease, compared to 22 percent in 1996.
Many Infected Herds
Among herds with 500 or more cows, the number of infected herds is at 95 percent, according to the USDA NAHMS survey. “The Wisconsin project used common sense management changes (See accompanying sidebar on reducing Johne’s disease risks.) to limit, as much as reasonably possible, the spread of Johne’s disease from cows to calves,” says Dr. Collins, an internationally recognized Johne’s disease expert. “We coupled this management plan to a testing program done once on every cow during every lactation, using the most accurate and low-cost test available at the time, the ELISA done on blood samples,” he says. “After six years, the percentage of test-positive cows in the herd was lower in all nine herds.
Some herds are on the verge of being 100 percent test-negative. The program was scientifically proven to be effective and producer-proven to be affordable.” Given what is known about the Johne’s disease situation today, Dr. Collins offers these important take-home messages:
- If your herd is not infected, avoid buying infected animals. In the U.S., roughly one in 20 dairy replacement animals purchased from random farm sources is infected with the cause of Johne’s disease, according to Dr. Collins.“Many will say the cost for doing this is too high or that it is impossible. I answer that the cost only seems highuntil your herd becomes infected. Then you realize how much more costly it is to control or eradicate the problem.”
- If your herd is infected, don’t despair. It is now known that the disease can be cost-effectively controlledusing field-tested methods. But it does take time—at least 6 years for effective control and probably twice that long for eradication, depending on how heavily infected the herd is in the first place.
- Don’t delay or avoid finding out if your herd is infected.
- If you do have Johne’s disease in your herd, take immediate steps and try to control it. If you don’t, the disease will slowly but surely spread until cull ratesare climbing, milk production is declining and profitability is disappearing. If you ignore this disease too long, and management can’t control the infection, it will put your dairy out of business, Dr. Collins emphasizes.
Diagnostic Tests
He explains that herd-level tests, such as environmental fecal culture, are simple, accurate and affordable. “Your Johne’s Certified Veterinarian can collect manure from six specific locations on the farm and establish if your herd is infected with M. paratuberculosis or has such a low level of infection that it is not a significant economic problem for the herd. The cost for sample collection and laboratory charges will be less than $300 for most typical herds.”
On the other hand, it is more expensive to establish by valid testing methods that a herd is not infected or of very low risk of being infected, according to Dr. Collins. “There are specific USDA rules and regulations for doing this and your Johne’s Certified Veterinarian or state’s Designated Johne’s Coordinator (DJC) has all the latest information.”
The University of Wisconsin demonstration herd project and other projects throughout the nation were partially funded from more than $100 million provided by USDA, Collins added. This money also was used for helping to develop new diagnostics, expand laboratory capacity, certify veterinarians, certify Johne’s disease diagnostic laboratories, create a scientifically sound herd risk assessment system, prove that control programs work and jump start herd testing by providing subsidies to producers. Dr. Collins believes that now is the time for the U.S. dairy industry to utilize the current information and programs to make a serious and concerted effort to get the upper hand on Johne’s disease. He provides the following examples of Johne’s disease programs that could be developed and implemented by the industry:
- Industry-driven programs with market incentives for sale of livestock and milk from herds that are on a Johne’s program.
- Breed organizations regulating themselves and requiring that animals sold through breed-sanctioned sales are test-negative. “They should set targets for the future to ‘raise the bar’ and create even stronger programs based on herd-level testing.”
- Cooperatives and processors setting standards that require every producer to certify that they have been educated and understand Johne’s disease. They could also require herds to have a Risk Assessment and Management Plan in place or offer to partially pay for animal-level testing as is being done in The Netherlands.
More Johne’s Disease Information Sources
Following are on-line sources of additional information about Johne’s disease:
• http://www.johnes.org/ University of Wisconsin School of Veterinary Medicine Johne’s Disease Information Center.
QUICK TIPS: Reducing Johne’s Disease Risks
Calf hygiene is crucial element of Johne’s disease risk management. Since most new Johne’s disease
infections happen before weaning, calf hygiene is critical to preventing and controlling the disease. Here are some herd management tips to help you reduce the risk of Johne’s disease in your herd:
- Cows should always calve in a clean pen.
- Only cows testing ELISA-negative for Mycobacterium paratuberculosis, the causative organism of Johne’s disease, should be used as colostrum donor cows.
- Thoroughly clean teats of colostrum donor cows before collecting colostrum.
- For newborn calves, administer at least four quarts of colostrum from one test-negative cow (three quartsfor Jerseys) within four hours after birth.
- Remove calves from the maternity pen as soon as possible after birth.
- House calves away from the cow herd.
- Maintain good hygiene practices, especially for heifer rearing.
- Ensure manure does not contaminate feed or water.
- Collect blood for Johne’s testing from lactating cows during the last third of their lactation.
- Cull all strong-positive testing cows before freshening.
- Visually identify all test-positive cows.
- Provide separate maternity pens for test-positive versus test-negative cows.
Colostrum Replacer: A Tool in Johne’s Control Programs
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Feeding
colostrum replacer can be an important tool in helping eliminate the risk of transmitting diseases, such as Johne’s, through maternal colostrum. When attempting to break a cycle of maternally transmitted disease, or when colostrum is in limited supply or of low quality, colostrum replacer has been proven to be a reliable management tool to help ensure that calves get a good start in life. In research trials, calves fed a colostrum replacer containing at least 125 grams of globulin protein within 24 hours after birth performed as well as calves fed maternal colostrum.1
In a University of Minnesota study, researchers found that plasma-derived colostrum-replacer feeding programs reduced the risk of Mycobacterium avium subsp. paratuberculosis (MAP) in Holstein calves born in Johne’s disease-endemic herds, implying that raw maternal colostrum might be a source of MAP infection for calves.2 In the study, 497 heifer calves from 12 MAP-endemic commercial dairy farms were fed either colostrum or colostrum replacer. Calves were followed to adulthood and tested for MAP infection. Calves fed colostrum replacer were 44 percent less likely to become infected by MAP (Johne’s disease) compared with calves fed maternalcolostrum at birth.
“This plasma colostrum replacement product is an effective management tool in dairy herds that are attempting to reduce the prevalence of Johne’s disease,” the study concluded.
References: 1. Kehoe, S, C Jones & AJ Heinrichs. Colostrum Supplements and Replacer. Department of Dairy and Animal Science, The Pennsylvania State University. DAS 05-103.
2. Pithua, P. et. al. - Efficacy of a Plasma Derived Commercial Colostrum Replacer Feeding Program for the Prevention of Transmission of Mycobacterium avium subsp. Paratuberculosis in Holstein Calves. Journal of the American Veterinary Medical Association Vol 234 (9):1167-76